The equipment enables measurement of optical probes in live, anaesthetized research animals. This requires fewer animals, thus reducing costs and increasing the validity of results.
The equipment is housed in the Department of Integrative Physiology and Neuroscience in the Veterinary and Biomedical Research Building. More information is available at http://ipn.vetmed.wsu.edu/equipment-resources/ivis-live-imaging.
Those interested in using the IVIS system may contact equipment manager David DeWitt at firstname.lastname@example.org.
The system is ideal for following the progress of tumor growth, spread and regression; tracking the distribution and growth of infectious agents; tracing how the body metabolizes drugs and monitoring the effects of drugs.
The IVIS instrument can measure bioluminescence, fluorescence and Cerenkov emissions from radio tracers. It has a CT scanner so the location and intensity of the optical probes can be registered in 3D.
The instrument was provided to the WSU research community by a grant from M. J. Murdock Charitable Trust.